polygenic risk score risk_factor_for schizophrenia

Subject: polygenic risk score
Relation: risk_factor_for
Object: schizophrenia
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences. (2021) PMID:33446638 primary

Genetic risk for SCZ, as measured by polygenic risk scores (PRS)...

confidence: 0.96

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

Statistically significant higher hazard rates for schizophrenia in the top PRS decile group.

confidence: 0.94