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Chrna4 interacts_with Chrnb2

Subject
Chrna4
Relation
interacts_with
Object
Chrnb2
p-value
Evidence from: primary | all sources

Evidence (7 sources)

Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain. (2018) PMID:30096299 cited
Expression of other gene pairs encoding heteromeric receptors ( ... Chrna4/Chrnb2) was also well correlated.
confidence: 0.94
Nominal association with CHRNA4 variants and nicotine dependence. (2013) PMID:23350800 cited
high affinity α4β2* receptor (where * indicates that it can combine with other subunits)
confidence: 0.95
Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. (2012) PMID:23040810 cited
heteromeric assemblies of α- and β-subunits (α2-α7 and β2-β4)
confidence: 0.85
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited
α4β2* subtype ... consists of both α and β subunits (α4 and β2).
confidence: 0.85
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited
α4 subunits form functional nAChR complexes with at least one β2 subunit
confidence: 0.94
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited
nAChRs that contain both α4 and β2 subunits are the most abundant in the brain
confidence: 0.96
Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011) PMID:21079997 cited
α4 and α5 nicotinic acetylcholine receptor (nAChR) subunits combine with the nAChR β2 subunit to form ... receptor
confidence: 0.95