OPRM1 associated_with opioid sensitivity
Evidence from:
primary |
all sources
Evidence (2 sources)
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
These three candidate genes, all associated with pain processing and opioid analgesia, were analyzed ... patients were classified as high, normal or non‑responders to the opioid remifentanil.
confidence: 0.94
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
A borderline significant association was found in an age and sex adjusted model of OPRM1 and opioid sensitivity (r = 0.188, adjusted R2 = 0.035 p = 0.106).
confidence: 0.60