SLC12A5 regulates GABA

Subject: SLC12A5
Relation: regulates
Object: GABA
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures. (2015) PMID:26250693 cited

KCC2 ... regulate intracellular chloride concentration ... determine whether GABA is inhibitory or excitatory

confidence: 0.90

Modeling hippocampal neurogenesis using human pluripotent stem cells. (2014) PMID:24672753 cited

upregulation of the KCC2 channel ... results in a transition from GABA‑excitatory to GABA‑inhibitory state

confidence: 0.90