NKX2-1 expressed_in medial ganglionic eminence

All neural progenitors, including MGE cells, ... were stained with primary antibody NKX2.1.

Transcription factors important for MGE specification were expressed at moderate to high levels (NKX2-1, ...)

mitotic MGE progenitors (NKX2-1+)

EGFP and NKX2-1 protein expression ... co-localized in a subset of cells derived from the MGE.

Nkx2-1 RNAs are maintained in the MGE

Nkx2-1 RNA and protein is expressed throughout the VZ and SVZ of the MGE

Nkx2.1-Cre; Zfhx1bF/- mutants were used, where Cre is driven by the Nkx2.1 promoter active in the MGE.

Nkx2-1 pathway is the core mediator of MGE regional and cell identity