GABAB receptor regulates Kcnj6

Subject: GABAB receptor
Relation: regulates
Object: Kcnj6
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome. (2017) PMID:28342823 cited

GABAB receptors mediate ‘slow’ type IPSCs via activation of Kir3.2 channels

confidence: 0.90

How inhibition shapes cortical activity. (2011) PMID:22017986 cited

GABAB receptors ... cause slow ... inhibition by opening inwardly rectifying K+ (GIRK) channels

confidence: 0.95