ALDH2 associated_with alcohol
Evidence from:
primary |
all sources
Evidence (10 sources)
Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood.
(2014)
PMID:23692184
primary
associations between ALDH2 and alcohol consumption among Asian-Americans also showed a parallel pattern with genetic effects becoming evident late in adolescence/young adulthood
confidence: 0.96
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
effect on average alcohol drinking of ... ALDH2
confidence: 0.70
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
identified 4 loci associated with alcohol consumption ... including ALDH2
confidence: 0.96
genetic variants play a known and relatively specific role in the pathway of interest (e.g., ALDH2 and alcohol consumption)
confidence: 0.90
Single variant approaches are appropriate when the genetic variants play a known and relatively specific role in the pathway of interest (e.g., ALDH2 and alcohol consumption).
confidence: 0.96
Polygenic risk scores for smoking: predictors for alcohol and cannabis use?
(2014)
PMID:24450588
cited
Among the top-hits are often alcohol dehydrogenase genes (... ALDH2) in alcohol GWAS.
confidence: 0.90
Polymorphisms in ALDH2 influence alcohol consumption.
confidence: 0.90
The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks.
(2012)
PMID:22348705
cited
ALDH2 ... influence alcohol consumption
confidence: 0.94
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
(2011)
PMID:21437268
cited
ALDH2 ... another key gene in alcohol metabolism.
confidence: 0.90
ALDH2 locus ... is associated with differences in both AD and alcohol consumption
confidence: 0.95