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OPRM1 risk_factor_for heavy drinking

Subject
OPRM1
Relation
risk_factor_for
Object
heavy drinking
p-value
Evidence from: primary | all sources

Evidence (2 sources)

KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex. (2016) PMID:26202629 primary
Down‑regulation of OPRM1 may play a role in increasing risk of heroin abuse
confidence: 0.90
Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. (2010) PMID:20520587 cited
role for five genes in the risk of developing heroin addiction including the gene coding for the μ opioid receptor
confidence: 0.95