genetic variants risk_factor_for CHD

Subject: genetic variants
Relation: risk_factor_for
Object: CHD
p-value: 0.004

Evidence from: primary | all sources

Evidence (1 sources)

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy. (2017) PMID:28960498 cited

The significant result for directional pleiotropy ... suggests that LDL‑C and triglycerides do not fully explain the direct effects of the genetic variants on the outcome.

confidence: 0.70