rs16969968 associated_with nicotine

Subject: rs16969968
Relation: associated_with
Object: nicotine
p-value: —

Evidence from: primary | all sources

Evidence (13 sources)

Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011) PMID:21079997 cited

univariate analysis of the COGEND data indicates that the genetic locus tagged by rs16969968 displays a highly significant association to nicotine dependence

confidence: 0.96

Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011) PMID:21079997 cited

Predictors included ... rs16969968 ... for nicotine dependence in the COGEND dataset.

confidence: 0.90

Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence. (2011) PMID:21079997 cited

these SNPs are strongly associated with nicotine dependence

confidence: 0.97

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. (2010) PMID:20584212 cited

three SNPs (rs16969968, rs578776, and rs588765) ... demonstrate association with nicotine dependence

confidence: 0.95

Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010) PMID:19896728 cited

Genetic association of rs16969968 reported repeatedly for nicotine dependence.

confidence: 0.88

Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes. (2010) PMID:20624154 cited

association between non-synonymous polymorphism on the nicotinic receptor gene CHRNA5 (rs16969968 ...) and nicotine dependence

confidence: 0.96

Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010) PMID:19896728 cited

To understand the biological relationship of the genetic association with nicotine dependence, lung cancer and COPD...

confidence: 0.88

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. (2010) PMID:20584212 cited

non-synonymous CHRNA5 SNP rs16969968 is significantly associated with nicotine dependence in AAs as well as in EAs

confidence: 0.95

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence. (2009) PMID:19132693 cited

we verified the association of rs16969968 ... with nicotine dependence when FTND scores were used as phenotype

confidence: 0.96

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

to account for the established effects of rs16969968

confidence: 0.85

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

rs16969968 ... is also significantly associated with nicotine dependence in African-Americans

confidence: 0.94

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

Both rs16969968 ... show strong association with nicotine dependence

confidence: 0.95

Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. (2008) PMID:18783506 cited

we focused our attention upon phenotype associations for the top 25 SNPs tested with nicotine dependence ... we decided to test rs16969968 a priori

confidence: 0.92