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CHRM2 associated_with alcohol dependence

Subject
CHRM2
Relation
associated_with
Object
alcohol dependence
p-value
Evidence from: primary | all sources

Evidence (9 sources)

Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. (2014) PMID:23362995 primary
CHRM2 is associated with a form of AD that is comorbid with drug dependence, but not with AD alone
confidence: 0.90
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
Significant linkage and association ... for diagnoses (DSM-IV and ICD-10) of alcohol dependence
confidence: 0.91
Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary
genetic determinants for ... alcohol dependence have been discovered ... CHRM2
confidence: 0.90
Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. (2009) PMID:18618593 primary
Recent evidence from COGA indicates that the CHRM2 gene is ... associated with ... alcohol dependence ...
confidence: 0.94
Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. (2006) PMID:17373405 primary
SNPs in the CHRM2 gene ... were associated with alcohol dependence
confidence: 0.90
The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. (2012) PMID:22348705 cited
Several candidate genes ... have been associated with alcohol dependence, including the genes encoding cholinergic receptor, muscarinic 2 (CHRM2).
confidence: 0.95
The genetics of alcohol dependence: advancing towards systems-based approaches. (2012) PMID:22854292 cited
the muscarinic receptor (CHRM2) has been replicated in two GWAS ... linked to alcohol use/alcoholism/AD
confidence: 0.90
An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back. (2011) PMID:34385894 cited
chromosome 7 ... had linkage to alcohol dependence diagnoses ... Just under the linkage peak was the gene CHRM2
confidence: 0.80
An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back. (2011) PMID:34385894 cited
two genes that we have focused on ... are GABRA2 and CHRM2 ... involved in alcohol dependence
confidence: 0.96