rs671 risk_factor_for alcohol flush reaction

Subject: rs671
Relation: risk_factor_for
Object: alcohol flush reaction
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017) PMID:28937693 cited

The catalytically inactive version of ALDH2 encoded by the A allele of rs671 leads to slower metabolism of acetaldehyde that causes the alcohol flush reaction.

confidence: 0.96