PKA regulates DARPP-32
Evidence from:
primary |
all sources
Evidence (5 sources)
PKA-mediated DARPP-32 phosphorylation
confidence: 0.94
PKA phosphorylates DARPP-32 on Thr-34, which renders DARPP-32 active as an inhibitor of PP-1.
confidence: 0.96
When PKA phosphorylates DARPP-32 on Thr-34, it serves as an inhibitor of PP-1.
confidence: 0.95
decrease PKA-mediated DARPP-32 phosphorylation.
confidence: 0.90
PKA and Cdk5 act on the same downstream target, DARPP-32, resulting in opposing effects.
confidence: 0.93