endophenotype associated_with psychiatric disorders
Evidence from:
primary |
all sources
Evidence (3 sources)
Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence.
(2009)
PMID:18618593
primary
These endophenotypes ... provide a more powerful strategy in searching for genes involved in producing psychiatric diagnoses.
confidence: 0.95
Heritability and molecular-genetic basis of resting EEG activity: a genome-wide association study.
(2014)
PMID:25387704
cited
one promise of endophenotypes — that they might help identify genes for psychiatric disorders — cannot yet be meaningfully assessed
confidence: 0.60
The neuroscience of suicidal behaviors: what can we expect from endophenotype strategies?
(2011)
PMID:21761009
cited
psychiatric diagnoses can be optimally deconstructed, resulting in more straightforward and successful genetic analysis
confidence: 0.90