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naltrexone protective_against Alcohol Use Disorder

Subject
naltrexone
Relation
protective_against
Object
Alcohol Use Disorder
p-value
Evidence from: primary | all sources

Evidence (3 sources)

Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol. (2020) PMID:32561311 primary
naltrexone ... decreases relapse in alcoholic individuals ... approved for the treatment of subjects with AUDs.
confidence: 0.85
Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review. (2018) PMID:30167705 cited
limited the use of naltrexone for treating AUD
confidence: 0.85
Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review. (2018) PMID:30167705 cited
Patients who meet criteria for an AUD should be prescribed ... naltrexone as initial therapy.
confidence: 0.95