Tbr1 biomarker_for schizophrenia

Subject: Tbr1
Relation: biomarker_for
Object: schizophrenia
p-value: 0.001

Evidence from: primary | all sources

Evidence (2 sources)

Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1. (2017) PMID:30446636 cited

Quantitative counting showed TBR1+ nuclei reduced in schizophrenia organoids (17.1% vs 32.2%, p < 0.001).

confidence: 0.92

Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1. (2017) PMID:30446636 cited

Decreased nuclear TBR1 expression in the upper cortical zone of 5‑week schizophrenia organoids.

confidence: 0.94