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PCSK9 associated_with LDL cholesterol

Subject
PCSK9
Relation
associated_with
Object
LDL cholesterol
p-value
1e-13
Evidence from: primary | all sources

Evidence (3 sources)

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. (2018) PMID:29739930 cited
PCSK9 yields colocalized signals for LDL-C levels in Tibial Nerve, Lung, and Whole blood.
confidence: 0.96
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. (2018) PMID:29739930 cited
highly significant association between PCSK9 and LDL-C (p ≈ 10⁻¹³) in visceral fat
confidence: 0.97
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics. (2018) PMID:29739930 cited
PCSK9 both for LDL-C and cardiovascular disease
confidence: 0.94