COMT risk_factor_for schizophrenia

Subject: COMT
Relation: risk_factor_for
Object: schizophrenia
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice. (2011) PMID:21223304 cited

COMT polymorphisms have been implicated in many disorders including schizophrenia

confidence: 0.92

Genetic and environmental factors in complex neurodevelopmental disorders. (2007) PMID:19412416 cited

The genes most often reported to be related to schizophrenia are the genes encoding ... catechol-O-methyl transferase (COMT ...).

confidence: 0.90