ADH4 risk_factor_for alcohol dependence
Evidence from:
primary |
all sources
Evidence (4 sources)
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
Three previously associated with alcohol dependence—ADH1B, ADH1C, and ADH4.
confidence: 0.97
Common biological networks underlie genetic risk for alcoholism in African- and European-American populations.
(2013)
PMID:23607416
primary
including the often replicated ... ADH4 ... have been implicated in alcoholism susceptibility
confidence: 0.95
genes in the ethanol metabolic pathway (e.g., ADH4 ...) are candidates for alcohol dependence
confidence: 0.95
The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks.
(2012)
PMID:22348705
cited
implicated as risk factors for developing alcohol abuse or dependence
confidence: 0.93