Chrnb4 associated_with heavy smoking
Evidence from:
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Evidence (4 sources)
the CHRNA5-A3-B4 gene cluster ... has been consistently shown to contain multiple loci strongly associated with heaviness of smoking
confidence: 0.92
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
genetic variants in the α5/α3/β4 nAChR gene cluster as associated with ... heaviness of smoking
confidence: 0.95
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence.
(2009)
PMID:19132693
cited
association between variants at the CHRNA5, CHRNA3, and CHRNB4 loci ... heavy smoking/nicotine dependence.
confidence: 0.90
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence.
(2009)
PMID:19132693
cited
CHRNB4 ... locus is associated with heavy smoking ...
confidence: 0.95