CTNND1 risk_factor_for OCD
Evidence from:
primary |
all sources
Evidence (2 sources)
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
(2025)
PMID:38712091
primary
CTNND1 was implicated by multiple approaches and showed evidence for colocalization, indicating it as a likely causal gene for OCD.
confidence: 0.94
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
(2025)
PMID:38712091
primary
downregulation of CTNND1 protein expression in human dorsolateral prefrontal cortex was significantly associated with OCD risk (Z = −4.49, P = 7.11 × 10⁻⁶)
confidence: 0.96