common variants risk_factor_for schizophrenia

large numbers of common alleles ... are genetic ... variation in risk ... associated with schizophrenia

both schizophrenia … much of it traces to common genetic variation.

common variation had 14–28 times more impact on risk for schizophrenia than rare CNVs or rare exonic variation

genes in schizophrenia GWAS associated regions overlap with those identified by sequencing studies

Genome-wide association studies ... increasing ... evidence for common SNPs contributing to schizophrenia risk.

common genetic variation accounted for far more of the variance in liability to schizophrenia than rare copy number variation or rare deleterious exonic variation

common SNPs of small effect ... contribute to schizophrenia risk and heritability.

Large Scale meta-analysis of GWAS has obtained statistically convincing evidence for common variants in schizophrenia

common alleles of ancient origin and with small to moderate effect lead to susceptibility to common disorders

supportive of the hypothesis that common variants contribute ... to schizophrenia