compound E targets γ-secretase
Evidence from:
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Evidence (6 sources)
Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector.
(2018)
PMID:29632371
cited
treated ... with an inhibitor of γ-secretase (compound E)
confidence: 0.95
Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells.
(2016)
PMID:27684569
cited
γ-Secretase inhibitor Compound E
confidence: 0.95
Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells.
(2016)
PMID:27684569
cited
γ-Secretase inhibitor Compound E is a widely used potent inhibitor for many in vitro and in vivo studies.
confidence: 0.96
Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells.
(2016)
PMID:27684569
cited
for γ-Secretase inhibitor Compound E ... the mass/charge (m/z) ratios monitored were ... for γ-Secretase inhibitor Compound E
confidence: 0.95
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.
(2016)
PMID:27622770
cited
γ-secretase inhibitor Compound E (Comp‑E …)
confidence: 0.98
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.
(2016)
PMID:27622770
cited
gamma secretases inhibitor (Compound E; EMD Millipore)
confidence: 0.96