rs1229984 associated_with alcohol
Evidence from:
primary |
all sources
Evidence (5 sources)
A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.
(2013)
PMID:23743675
primary
identified a SNP (rs1229984) ... strongly associated with lower consumption of alcohol
confidence: 0.95
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
ADH1B rs1229984 ... largest impact on alcohol consumption
confidence: 0.93
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
both genetic polymorphisms ADH1B rs1229984 and ALDH2 rs671 ... significantly influence drinking behavior in a synergistic manner.
confidence: 0.95
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
(2011)
PMID:21437268
cited
minor allele carriers of rs1229984 reported consuming less alcohol than non-carriers (p = 3×10−20)
confidence: 0.96
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
(2011)
PMID:21437268
cited
suggesting the effect with the rs1229984 variant is mediated through alcohol drinking rather than tobacco smoking.
confidence: 0.88