FGFR1 associated_with schizophrenia
Evidence from:
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Evidence (5 sources)
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
The loss of nFGFR1 ... observed in schizophrenia organoids likely underlies the impaired neuronal differentiation and cortical maldevelopment observed in schizophrenia.
confidence: 0.80
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
overexpression in schizophrenia iPSC-derived NPCs was shown in ref. 55
confidence: 0.94
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
FGFR1 expression in the CZ was greatly reduced in schizophrenia organoids compared to controls.
confidence: 0.92
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
the role of FGFR1 in schizophrenia
confidence: 0.90
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
The importance of these genomic findings transcends the current investigation centered on schizophrenia.
confidence: 0.70