heavy drinking risk_factor_for opioid dependence
Evidence from:
primary |
all sources
Evidence (2 sources)
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond.
(2022)
PMID:36207451
primary
exposure to opioids ... differs in risk of OA from exposure to illicit heroin use
confidence: 0.90
From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics.
(2009)
PMID:19214139
cited
Addiction to illicit and prescription opioid narcotic drugs (heroin, morphine, codeine, oxycodone ...) is a significant public health issue.
confidence: 0.95