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CACNA1C risk_factor_for Timothy syndrome

Subject
CACNA1C
Relation
risk_factor_for
Object
Timothy syndrome
p-value
Evidence from: primary | all sources

Evidence (3 sources)

Assembly of functionally integrated human forebrain spheroids. (2017) PMID:28445465 cited
gain-of-function mutations in the LTCCs-encoding CACNA1C gene lead to Timothy syndrome
confidence: 0.95
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. (2009) PMID:19065143 cited
mutations in this gene are already known to cause Timothy Syndrome
confidence: 0.90
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. (2009) PMID:19065143 cited
mutations in this gene are already known to cause Timothy Syndrome
confidence: 0.95