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Post-Traumatic Stress Disorder associated_with mood disorders

Subject
Post-Traumatic Stress Disorder
Relation
associated_with
Object
mood disorders
p-value
2e-16
Evidence from: primary | all sources

Evidence (3 sources)

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. (2024) PMID:38637617 primary
the genetic correlation of PTSD with MDD is as high or higher than genetic correlations between different cohorts...
confidence: 0.95
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. (2024) PMID:38637617 primary
overall strong rg between PTSD and MDD (rg = 0.85, s.e. = 0.008, P < 2 × 10−16)
confidence: 0.99
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. (2024) PMID:38637617 primary
The strong majority (79–99%) of the variation influencing PTSD risk also influenced these disorders; PTSD had the highest fraction of concordant effect directions with MDD (87% concordant).
confidence: 0.97