OPRM1 A118G associated_with fentanyl
Evidence from:
primary |
all sources
Evidence (2 sources)
G/G individuals requiring more ... fentanyl to achieve analgesia
confidence: 0.92
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
fentanyl is less effective in subjects carrying the G allele of the OPRM1 A118G SNP and they require more fentanyl for adequate postoperative pain control
confidence: 0.93