DISC1 risk_factor_for schizophrenia
Evidence from:
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Evidence (4 sources)
DISC1 was rated as highly likely to be a genetic risk factor for schizophrenia (rating ≥4 on a 1–5 scale).
confidence: 0.95
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
(2014)
PMID:23732877
cited
the translocation that disrupts DISC1 ... associated with diagnoses of SZ, BP and rMDD.
confidence: 0.85
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
(2014)
PMID:23732877
cited
Case–control association was tested ... individually for SZ ... using Fisher's exact test.
confidence: 0.90
Genetic and environmental factors in complex neurodevelopmental disorders.
(2007)
PMID:19412416
cited
The genes most often reported to be related to schizophrenia are the genes encoding disrupted in schizophrenia 1 (DISC1 ...).
confidence: 0.90