CYP2A6 associated_with nicotine metabolism

Subject: CYP2A6
Relation: associated_with
Object: nicotine metabolism
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism. (2015) PMID:26407342 cited

CYP2A6, the gene encoding the main metabolic enzyme for nicotine

confidence: 0.98

Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited

Null or reduced activity CYP2A6 alleles ... are associated with slower metabolism

confidence: 0.85

Genome-wide and candidate gene association study of cigarette smoking behaviors. (2009) PMID:19247474 cited

relationship between CYP2A6 genetic variation and ... nicotine metabolism

confidence: 0.90