EP300 biomarker_for alcohol dependence

Subject: EP300
Relation: biomarker_for
Object: alcohol dependence
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (2011) PMID:21184583 primary

reductions in P300 amplitude ... foremost being alcohol dependence

confidence: 0.90

Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. (2009) PMID:18618593 primary

genetic analysis of P300 amplitude data ... has revealed significant linkage ... with alcohol dependence.

confidence: 0.94