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naltrexone protective_against drinking

Subject
naltrexone
Relation
protective_against
Object
drinking
p-value
Evidence from: primary | all sources

Evidence (3 sources)

Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
reduces the number of drinking days (O’Malley et al., 1992, Volpicelli et al., 1992)
confidence: 0.96
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
naltrexone reduces the number of drinking days
confidence: 0.95
The genetics of the opioid system and specific drug addictions. (2012) PMID:22547174 cited
Both antagonists reduce drinking and craving in alcoholic individuals in treatment and also in heavy drinkers.
confidence: 0.95