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rs578776 associated_with European ancestry

Subject
rs578776
Relation
associated_with
Object
European ancestry
p-value
0.0055
Evidence from: primary | all sources

Evidence (2 sources)

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans. (2010) PMID:20584212 cited
variation explained by the chromosome 15q25 SNPs rs578776 ... is 1.9% in both EAs and AAs.
confidence: 0.90
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited
tested for association of rs578776 ... remains significant (p-value 0.0055, OR = 0.80 (0.68–0.94))
confidence: 0.96