Fgf21 interacts_with Klb
Evidence from:
primary |
all sources
Evidence (5 sources)
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
(2019)
PMID:30336701
cited
as part of a receptor complex with β‑Klotho (KLB)
confidence: 0.90
adipose tissue and adipocyte FGFR1‑KLB is the primary tissue and molecular target of inter‑organ messenger FGF21
confidence: 0.95
FGF21-FGFR1-KLB mediated uncoupling
confidence: 0.93
Activity of FGF21 is determined by a transmembrane co‑receptor betaKlotho (KLB).
confidence: 0.96
FGF21 promotes metabolic homeostasis via white adipose and leptin in mice.
(2012)
PMID:22792234
cited
FGF21 binds fibroblast growth factor receptor (FGFR) tyrosine kinases complexed with the co-receptor β‑klotho
confidence: 0.95