substance use associated_with depression

substance use disorders were more strongly associated with depression for those over age 30 compared to those under age 30

co-occurrence of substance use and depression ... individuals with co-occurring disorders ... Our results demonstrate significant associations between substance use behaviors and depressive symptoms throughout adolescence and young adulthood

Although the co-occurrence of substance use behaviors and depression is well-established... the associations between substance use behaviors and depression are also stronger during adolescence.

SUDs are frequently comorbid with other mental illnesses including ... depression ...