gabapentin targets CACNA2D2

Subject: gabapentin
Relation: targets
Object: CACNA2D2
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects. (2013) PMID:23402298 cited

The α2δ fragment is also the effect site for gabapentin and pregabalin

confidence: 0.95