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N/OFQ protective_against alcohol self-administration

Subject
N/OFQ
Relation
protective_against
Object
alcohol self-administration
p-value
Evidence from: primary | all sources

Evidence (4 sources)

Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. (2012) PMID:23040815 cited
Wistar rats ... were more sensitive to the alcohol intake-reducing actions of N/OFQ
confidence: 0.90
Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. (2012) PMID:23040815 cited
alcohol self-administration is reduced by site-specific injections of N/OFQ into the central amygdala
confidence: 0.95
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. (2009) PMID:19913192 cited
subchronic administration of N/OFQ ... significantly reduces ethanol self-administration in ... msP rats
confidence: 0.96
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. (2009) PMID:19913192 cited
activation of NOP receptors by N/OFQ has been shown to inhibit ... operant ethanol self-administration
confidence: 0.94