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coga / coga-kb
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alcohol regulates IKBKB

Subject
alcohol
Relation
regulates
Object
IKBKB
p-value
Evidence from: primary | all sources

Evidence (2 sources)

The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009) PMID:19561104 cited
Acute alcohol ... decreased IKK kinase activity; chronic alcohol ... increased IKK kinase activity.
confidence: 0.94
The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009) PMID:19561104 cited
up-regulation of IKK kinase activity leading to augmentation of LPS-induced NFκB binding
confidence: 0.85