cocaine regulates Cdk5

increase in the expression of their associated proteins after chronic cocaine exposure

chronic cocaine treatment induced marked increases in acetylation state ... of the Cdk5 gene

Chronic administration of cocaine increases Cdk5 activity

Repeated cocaine injections ... increase Cdk5 levels ... in the rat dorsal striatum and NAc.

Repeated exposure to cocaine increases Cdk5 levels

In rats, chronic exposure to cocaine increases the level of Cdk5 in the striatum