OPRM1 associated_with opioid
Evidence from:
primary |
all sources
Evidence (3 sources)
Activation of MOR or DOR results in rewarding effects and analgesia.
confidence: 0.94
genetic variants ... associated with pharmacogenetic effects in analgesia (bolded)
confidence: 0.95
Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR).
(2010)
PMID:20336438
cited
opioid-induced analgesia is a consequence of inhibitory cellular effects resulting from the binding of μ-opioid agonists to MOR
confidence: 0.93