polygenic risk score associated_with African American

Subject: polygenic risk score
Relation: associated_with
Object: African American
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

The Impact of Polygenic Risk, Parental Separation, and Parental Relationship Discord on Heavy Episodic Drinking Across Adolescence and Young Adulthood in a High-Risk Sample. (2025) PMID:41367971 primary

African ancestry–derived polygenic scores

confidence: 0.93

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. (2021) PMID:34002096 cited

PRS explained up to 1.2% and 0.4% of variance in BD in two admixed African American samples.

confidence: 0.90