Chrnb4 associated_with cigarettes
Evidence from:
primary |
all sources
Evidence (3 sources)
KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex.
(2016)
PMID:26202629
primary
Genetic associations have been established for CHRNA5/A3/B4 polymorphisms with cigarette smoking
confidence: 0.95
genes ... have been firmly established ... in other studies of nicotine dependence and related smoking phenotypes
confidence: 0.70
Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence.
(2011)
PMID:21079997
cited
The α5α3β4 cholinergic nicotinic receptor cluster ... is now unequivocally associated with ... the number of cigarettes smoked per day.
confidence: 0.95