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GCKR associated_with alcohol

Subject
GCKR
Relation
associated_with
Object
alcohol
p-value
Evidence from: primary | all sources

Evidence (12 sources)

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019) PMID:30940813 primary
Risk genes identified in this study included GCKR
confidence: 0.90
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019) PMID:30940813 primary
Five of the loci were previously associated with a self-reported measure of alcohol consumption: GCKR, KLB, ADH1B, ADH1C, and SLC39A8.
confidence: 0.96
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
GCKR ... has been previously associated with alcohol consumption
confidence: 0.93
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
identified numerous loci ... that influence alcohol consumption, including ... GCKR, encoding the glucokinase regulatory protein
confidence: 0.94
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
association between rs1260326 in the gene GCKR and alcohol consumption
confidence: 0.80
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017) PMID:28937693 cited
Novel loci found to be associated with alcohol consumption in this study include GCKR...
confidence: 0.96
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017) PMID:28485404 cited
the second locus with genome-wide significance was near GCKR ... influencing alcohol consumption
confidence: 0.95
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017) PMID:28937693 cited
GCKR ... significantly associated with alcohol consumption.
confidence: 0.95
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017) PMID:28485404 cited
GCKR ... SNPs ... contribute to alcohol consumption
confidence: 0.95
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017) PMID:28485404 cited
identified 4 loci associated with alcohol consumption ... including GCKR
confidence: 0.96
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017) PMID:28937693 cited
Novel hits included a SNP on chromosome 2p23.3 in the GCKR gene.
confidence: 0.93
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017) PMID:28937693 cited
novel loci (GCKR ... ) in the context of alcohol consumption
confidence: 0.95