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brain associated_with schizophrenia

Subject
brain
Relation
associated_with
Object
schizophrenia
p-value
Evidence from: primary | all sources

Evidence (4 sources)

Mapping genomic loci implicates genes and synaptic biology in schizophrenia. (2022) PMID:35396580 cited
cis-eQTL summary data were from three studies: ... adult brain (n = ~1,500) ... to identify SNPs which might mediate association with schizophrenia
confidence: 0.90
Mapping genomic loci implicates genes and synaptic biology in schizophrenia. (2022) PMID:35396580 cited
genes with high specificity for expression in almost all tested brain regions are enriched for genetic association.
confidence: 0.93
Mapping genomic loci implicates genes and synaptic biology in schizophrenia. (2022) PMID:35396580 cited
we used summary-based Mendelian randomisation ... to find evidence that GWAS signals co-localise with eQTLs (from adult brain ... )
confidence: 0.90
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. (2018) PMID:29632380 cited
identify strong enrichments such as brain enrichment for schizophrenia
confidence: 0.95