RXR regulates CYP2E1

Subject: RXR
Relation: regulates
Object: CYP2E1
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009) PMID:19756185 cited

RXR may play an important role in P450 regulation at the transcription and translational levels.

confidence: 0.80

Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009) PMID:19756185 cited

RXR may regulate CYP2E1; in RXR KO mice CYP2E1 activity is reduced and not induced by ethanol.

confidence: 0.60