rs1051730 associated_with Chrna3
Evidence from:
primary |
all sources
Evidence (4 sources)
Genetic variability in the regulation of gene expression in ten regions of the human brain.
(2014)
PMID:25174004
cited
It is a synonymous exonic SNP located in CHRNA3
confidence: 0.97
TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood.
(2011)
PMID:21168125
cited
the most significant SNP was rs1051730 (P=1.1×10−5) mapping in CHRNA3
confidence: 0.90
Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence.
(2009)
PMID:19132693
cited
Markers with positive reports of association ( ... rs1051730) were included for the interval covering the CHRNA5, CHRNA3, and CHRNB4 genes.
confidence: 0.90
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
(2009)
PMID:19429911
cited
rs1051730 SNP in the CHRNA5–CHRNA3–CHRNB4 gene cluster
confidence: 0.95