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DRD3 associated_with cocaine

Subject
DRD3
Relation
associated_with
Object
cocaine
p-value
Evidence from: primary | all sources

Evidence (2 sources)

The aggregate effect of dopamine genes on dependence symptoms among cocaine users: cross-validation of a candidate system scoring approach. (2012) PMID:22358648 primary
The optimal risk score ... incorporated four SNPs (one each from four separate genes: DBH, DRD1, DRD3, and DRD4) and explained 0.55% of the sample variance in the “testing” sample (p = 0.037).
confidence: 0.90
Genetic and environmental factors in complex neurodevelopmental disorders. (2007) PMID:19412416 cited
genetic variations in the DRD3 ... have been reported to associate with cocaine abuse
confidence: 0.95