fenofibrate targets PPARα

Subject: fenofibrate
Relation: targets
Object: PPARα
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. (2015) PMID:25516156 primary

brain levels attained are likely high enough to activate PPARα but not other PPARs

confidence: 0.90

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. (2016) PMID:26838599 cited

PPARα agonist fenofibrate

confidence: 0.96