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ALDH2 interacts_with alcohol

Subject
ALDH2
Relation
interacts_with
Object
alcohol
p-value
Evidence from: primary | all sources

Evidence (6 sources)

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
genes that influence pharmacokinetic (e.g. ADH1B, ADH1C, ALDH2)
confidence: 0.92
Genetic studies of alcohol dependence in the context of the addiction cycle. (2017) PMID:28118990 cited
genes encoding the alcohol metabolizing enzymes ... include ALDH2.
confidence: 0.92
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017) PMID:28485404 cited
genes in the alcohol metabolism pathway, specifically, aldehyde dehydrogenase 2 (ALDH2).
confidence: 0.70
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017) PMID:28485404 cited
ALDH2 ... play a central role in the metabolism of alcohol in humans
confidence: 0.95
Gene-environment interactions in cancer epidemiology: a National Cancer Institute Think Tank report. (2013) PMID:24123198 cited
ALDH2, alcohol and esophageal cancer ... examples of successes
confidence: 0.90
An Interdisciplinary Approach to Studying Gene-Environment Interactions: From Twin Studies to Gene Identification and Back. (2011) PMID:34385894 cited
genes encoding alcohol metabolizing enzymes: aldehyde dehydrogenase (ALDH)...
confidence: 0.70